SCHEMBL6275085

SCHEMBL6275085

CC1(c2cccs2)OCCNc2ccc(-c3cc(F)cc(F)c3)cc21

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGR P06401 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3987006 0.84 PGR (0.76) PGR
SCHEMBL6264525 0.82 PGR (0.48) PGR
SCHEMBL3983061 0.81 PGR (0.44) PGR
SCHEMBL3986718 0.79 PGR (0.75) PGR
SCHEMBL3981544 0.78 PGR (0.80) PGR
SCHEMBL3983171 0.77 PGR (0.77) PGR
SCHEMBL6278198 0.73 PGR (0.70) PGR
SCHEMBL3990369 0.71 PGR (1.00) PGR
SCHEMBL3985103 0.70 PGR (0.81) PGR
SCHEMBL3985077 0.69 PGR (0.71) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005095366-A1 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS WYETH (US) 2005-10-13 WO claimed
WO-2005095366-A1 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS WYETH (US) 2005-10-13 WO disclosed