Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 19/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274593 | 0.91 | ADAMTS5 (0.54) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL6277257 | 0.73 | ADAMTS5 (0.58) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL4351836 | 0.73 | ADAMTS5 (1.00) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL6262704 | 0.71 | ADAMTS5 (0.49) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL4192767 | 0.70 | ADAMTS5 (1.00) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL6265250 | 0.67 | ADAMTS5 (0.45) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL6275124 | 0.67 | ADAMTS5 (0.45) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL6274347 | 0.66 | ADAMTS5 (0.47) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL4343954 | 0.66 | ADAMTS5 (1.00) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL15928247 | 0.65 | ADAMTS5 (0.78) | ADAMTS5ALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |