Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | RAD52 | P43351 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HEXA | P06865 | 3/20 | 0.58 |
| ▸ | HEXB | P07686 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275178 | 0.93 | KDM4E (0.69) | KDM4ERXFP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6272682 | 0.86 | MAPT (0.73) | KDM4ERXFP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8556230 | 0.85 | GRM5 (0.66) | KDM4EALDH1A1RAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL27657032 | 0.84 | GRM5 (0.64) | KDM4EALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2619579 | 0.84 | KDM4E (0.64) | KDM4ERXFP1ALDH1A1RAB9AMEN1 | |
| SCHEMBL11623083 | 0.84 | HEXA (0.74) | KDM4ERXFP1ALDH1A1RAB9AMEN1 | |
| SCHEMBL11441512 | 0.83 | MEN1 (0.83) | KDM4ERXFP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11632287 | 0.83 | HTR7 (0.70) | KDM4ERXFP1ALDH1A1MEN1KMT2A | |
| SCHEMBL11690758 | 0.81 | RAD52 (0.64) | KDM4ERXFP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12133960 | 0.81 | CYP1B1 (0.60) | KDM4ERXFP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041202-B | Preparation method of 1, 8-disubstituted naphthalene mononitration derivative | 长江大学 | 2022-04-19 | — | — | CN | claimed |
| CN-110041203-A | A kind of 1,8- bis- replaces the preparation method of naphthalene system condensed-nuclei aromatics mono-nitration derivative | 长江大学 | 2019-07-23 | — | — | CN | claimed |
| CN-107325095-B | A kind of lysosome hypochlorous acid fluorescence probe and its preparation method and application | 济南大学 | 2019-03-15 | — | — | CN | claimed |
| CN-106008342-B | A kind of fluorescence probe and preparation method thereof detecting formaldehyde in cytase body | 济南大学 | 2018-08-21 | — | — | CN | claimed |
| CN-106008342-A | Fluorescent probe for detecting formaldehyde in cytolysosome and preparation method thereof | 济南大学 | 2016-10-12 | — | — | CN | claimed |
| CN-112939935-B | Lysosome targeted fluorescent probe, synthetic method thereof and cell imaging application | 中国科学院大连化学物理研究所 | 2022-11-15 | — | — | CN | disclosed |
| CN-110041202-B | Preparation method of 1, 8-disubstituted naphthalene mononitration derivative | 长江大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-110041202-A | A kind of 1,8- bis- replaces the preparation method of naphthalene mono-nitration derivative | 长江大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-110041203-A | A kind of 1,8- bis- replaces the preparation method of naphthalene system condensed-nuclei aromatics mono-nitration derivative | 长江大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-106008342-B | A kind of fluorescence probe and preparation method thereof detecting formaldehyde in cytase body | 济南大学 | 2018-08-21 | — | — | CN | disclosed |
| CN-106008342-B | A kind of fluorescence probe and preparation method thereof detecting formaldehyde in cytase body | 济南大学 | 2018-08-21 | — | — | CN | disclosed |
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| EP-2085766-A2 | Method for identifying electrophiles and nucleophiles in a sample | Technion Research and Development Foundation, Ltd. (IL) | 2009-08-05 | — | — | EP | disclosed |
| US-20050239833-A1 | Compositions and methods for modulating interaction between polypeptides | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2005-10-27 | — | — | US | disclosed |
| WO-2005087217-A1 | COMPOSITIONS AND METHODS FOR MODULATING INTERACTION BETWEEN POLYPEPTIDES | THE GENERAL HOSPITAL CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005053663-A2 | NOREPINEPHRINE REUPTAKE INHIBITORS USEFUL FOR TREATMENT OF COGNITIVE FAILURE | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239833-A1 | Compositions and methods for modulating interaction between polypeptides | IAPP, SERPINA6, SERPINA2 | KDM4E 4859/4885RXFP1 1823/4885ALDH1A1 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.