Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276296 | 0.88 | TSHR (0.37) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL11720051 | 0.84 | TSHR (0.46) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL3164866 | 0.82 | TSHR (0.32) | TSHRGAADGAT1 | |
| SCHEMBL783556 | 0.82 | ALDH1A1 (0.35) | TSHRGAADGAT1ALDH1A1 | |
| SCHEMBL7089134 | 0.81 | ALDH1A1 (0.32) | TSHRTET2ALDH1A1 | |
| SCHEMBL610468 | 0.80 | TSHR (0.44) | TSHRGAARECQLALDH1A1 | |
| SCHEMBL10918514 | 0.80 | TSHR (0.50) | TSHRRECQLALDH1A1MEN1KMT2A | |
| SCHEMBL10922395 | 0.78 | TSHR (0.42) | TSHRGAARECQLALDH1A1KMT2A | |
| SCHEMBL783992 | 0.78 | ALDH1A1 (0.48) | TSHRRECQLALDH1A1 | |
| SCHEMBL11720062 | 0.77 | EGLN1 (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050123781-A1 | One-component flexible etch resistant clearcoat | NIPPON PAINT (USA), INC. | 2005-06-09 | — | — | US | disclosed |
| EP-1538172-A1 | One-component flexible etch resistant clearcoat | ROHM AND HAAS COMPANY (US) | 2005-06-08 | — | — | EP | disclosed |