Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909392 | 0.87 | PGR (0.48) | PGRNR3C1NR3C2AR | |
| SCHEMBL6772819 | 0.86 | PGR (0.54) | PGR | |
| SCHEMBL7686696 | 0.84 | PGR (0.74) | PGRNR3C1NR3C2AR | |
| SCHEMBL3874234 | 0.81 | PGR (0.72) | PGRNR3C1 | |
| SCHEMBL3991099 | 0.74 | PGR (0.74) | PGRNR3C1NR3C2AR | |
| SCHEMBL6433927 | 0.74 | PGR (0.72) | PGR | |
| SCHEMBL3986855 | 0.73 | PGR (0.64) | PGRNR3C1NR3C2AR | |
| SCHEMBL6408891 | 0.73 | PGR (0.73) | PGR | |
| SCHEMBL1223535 | 0.73 | PGR (0.49) | PGR | |
| SCHEMBL4911165 | 0.72 | PGR (0.68) | PGRNR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |