Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346019 | 0.83 | KMT2A (0.76) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6277055 | 0.83 | MAPT (0.73) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6279578 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6273823 | 0.82 | KMT2A (1.00) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6281550 | 0.82 | KMT2A (0.86) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6274351 | 0.80 | MEN1 (0.80) | ALDH1A1MAPTLMNANPSR1MEN1 | |
| SCHEMBL6279510 | 0.80 | KMT2A (0.73) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6273841 | 0.79 | KMT2A (0.69) | ALDH1A1MAPTLMNANPSR1MEN1 | |
| SCHEMBL6280499 | 0.77 | ALDH1A1 (0.76) | ALDH1A1MAPTPOLBLMNANPSR1 | |
| SCHEMBL6279502 | 0.76 | KMT2A (0.73) | ALDH1A1MAPTLMNANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005115147-A2 | HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2005-12-08 | — | — | WO | disclosed |