SCHEMBL6277078

SCHEMBL6277078

O=C(C(O)(c1ccccc1)c1ccccc1O)C(O)(c1ccccc1)c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.47
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KIF11 P52732 1/20 0.43
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
HTT P42858 3/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618641 0.88 CYP2C9 (0.57) CYP2C9ALDH1A1TSHRTDP1KIF11
SCHEMBL9056652 0.80 CYP2C9 (0.54) CYP2C9SMN1; SMN2HTTLMNAL3MBTL1
Benzylic Acid SCHEMBL7066 0.75 CYP2C9 (0.74) CYP2C9ALDH1A1TSHRSMN1; SMN2HTT
SCHEMBL30445305 0.74 ALDH1A1 (0.50) CYP2C9ALDH1A1TSHRTDP1KIF11
SCHEMBL2241764 0.74 ALDH1A1 (0.50) CYP2C9ALDH1A1TSHRTDP1KIF11
SCHEMBL8583178 0.74 ALDH1A1 (0.50) CYP2C9ALDH1A1TSHRTDP1KIF11
Benzylic Acid SCHEMBL11049826 0.73 CYP2C9 (0.71) CYP2C9ALDH1A1TSHRSMN1; SMN2HTT
Benzylic Acid SCHEMBL9181980 0.73 CYP2C9 (0.71) CYP2C9ALDH1A1TSHRSMN1; SMN2HTT
Benzylic Acid SCHEMBL1680669 0.73 CYP2C9 (0.71) CYP2C9ALDH1A1TSHRSMN1; SMN2HTT
Benzylic Acid SCHEMBL20957595 0.73 CYP2C9 (0.71) CYP2C9ALDH1A1TSHRSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9157268-A None JP disclosed
EP-0994093-B1 POLYHYDROXYPHENOL DERIVATIVES AND PREVENTIVE AND THERAPEUTIC AGENTS FOR BONE AND CARTILAGE DISEASES CONTAINING THE SAME HOECHST MARION ROUSSEL LTD (JP) 2005-12-28 EP disclosed
JP-H09157268-A PRODUCTION OF 7-HYDROXYISOFLAVONE AND ITS PURIFICATION NIPPON KAYAKU CO LTD 1997-06-17 JP disclosed