Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394617 | 0.90 | HTR2A (0.52) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL2397708 | 0.85 | HTR2A (0.52) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL2395338 | 0.82 | HTR2A (0.49) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL30221714 | 0.82 | HTR2A (0.51) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL6395093 | 0.81 | HTR2A (0.62) | HTR2AALDH1A1GAAKDM4EMGLL | |
| SCHEMBL13736848 | 0.81 | HTR2A (0.55) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL23056443 | 0.80 | HTR2A (0.54) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL8410730 | 0.80 | HTR2A (0.54) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL29629121 | 0.80 | HTR2A (0.54) | HTR2ABCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL9140032 | 0.80 | HTR2A (0.57) | HTR2ABCL9CTNNB1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077962-B1 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | US GOV HEALTH & HUMAN SERV (US) | 2005-04-13 | — | — | EP | claimed |
| US-6656737-B1 | Reacting 9-anthracenemethanol, pyridine, and p-nitrophenyl chloroformate; reacting the product with an amine, especially piperazine, to form a product that can be used to determine the total amount of isocyanate in a sample | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-12-02 | — | — | US | claimed |
| EP-1077962-A2 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by The Secretary, Department of Health and Human Services (US) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058517-A2 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-11-18 | — | — | WO | claimed |
| EP-1077962-B1 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | US GOV HEALTH & HUMAN SERV (US) | 2005-04-13 | — | — | EP | disclosed |
| US-6656737-B1 | Reacting 9-anthracenemethanol, pyridine, and p-nitrophenyl chloroformate; reacting the product with an amine, especially piperazine, to form a product that can be used to determine the total amount of isocyanate in a sample | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-12-02 | — | — | US | disclosed |
| EP-1077962-A2 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by The Secretary, Department of Health and Human Services (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058517-A2 | ISOCYANATE DERIVATIZING AGENT AND METHODS OF PRODUCTION AND USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-11-18 | — | — | WO | disclosed |