Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837611 | 0.91 | P2RX7 (0.43) | P2RX7CNR1CNR2 | |
| SCHEMBL5839014 | 0.88 | P2RX7 (0.49) | P2RX7CNR1CNR2 | |
| SCHEMBL5838143 | 0.88 | P2RX7 (0.49) | P2RX7CNR1CNR2 | |
| SCHEMBL5837101 | 0.83 | P2RX7 (0.48) | P2RX7CNR1CNR2 | |
| SCHEMBL6277402 | 0.81 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL5839038 | 0.80 | P2RX7 (0.49) | P2RX7CNR1CNR2 | |
| SCHEMBL5837842 | 0.79 | CNR1 (0.42) | P2RX7CNR1CNR2 | |
| SCHEMBL5837945 | 0.79 | P2RX7 (0.42) | P2RX7CNR1CNR2 | |
| SCHEMBL5838398 | 0.79 | P2RX7 (0.49) | P2RX7CNR1CNR2 | |
| SCHEMBL5838241 | 0.78 | P2RX7 (0.41) | P2RX7CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581507-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | Pfizer Products Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058731-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2004-07-15 | — | — | WO | disclosed |