Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327324 | 1.00 | HSP90AA1 (0.45) | HSP90AA1LAP3PNMTADRA2AMEN1 | |
| Hydrochloric Acid SCHEMBL8176659 | 0.98 | LAP3 (0.47) | HSP90AA1LAP3PNMTADRA2AMEN1 | |
| Hydrochloric Acid SCHEMBL8685041 | 0.91 | LAP3 (0.48) | LAP3MEN1KMT2AGRIN2B | |
| SCHEMBL6478814 | 0.90 | HSP90AA1 (0.47) | HSP90AA1PNMTADRA2AMEN1LMNA | |
| SCHEMBL30073945 | 0.90 | HSP90AA1 (0.47) | HSP90AA1PNMTADRA2AMEN1LMNA | |
| SCHEMBL2244560 | 0.87 | LAP3 (0.48) | HSP90AA1LAP3PNMTADRA2AMEN1 | |
| SCHEMBL4870044 | 0.81 | HSP90AA1 (0.44) | HSP90AA1PNMTADRA2AMEN1LMNA | |
| SCHEMBL6359153 | 0.81 | HSP90AA1 (0.44) | HSP90AA1PNMTADRA2AMEN1LMNA | |
| SCHEMBL4873492 | 0.81 | HSP90AA1 (0.44) | HSP90AA1PNMTADRA2AMEN1LMNA | |
| SCHEMBL6575270 | 0.81 | HSP90AA1 (0.44) | HSP90AA1PNMTADRA2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005084205-A2 | DIAMINO THIAZOLOINDAN DERIVATIVES AND THEIR USE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2005-09-15 | — | — | WO | disclosed |