Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277898 | 1.00 | MAOB (0.46) | MAOBMAOAPKMGPR55FBP1 | |
| SCHEMBL600337 | 0.87 | MAOB (0.55) | MAOBPKMGPR55MEN1KMT2A | |
| SCHEMBL600336 | 0.87 | MAOB (0.55) | MAOBPKMGPR55MEN1KMT2A | |
| SCHEMBL11224609 | 0.83 | MAOB (0.59) | MAOBPKMGPR55MEN1KMT2A | |
| SCHEMBL11224607 | 0.83 | MAOB (0.59) | MAOBPKMGPR55MEN1KMT2A | |
| SCHEMBL11224613 | 0.83 | MAOB (0.59) | MAOBPKMGPR55MEN1KMT2A | |
| SCHEMBL6285273 | 0.83 | MAOB (0.50) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL6285284 | 0.83 | MAOB (0.50) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL622906 | 0.81 | AKR1C1 (0.62) | PKMFBP1MEN1KMT2AALDH1A1 | |
| SCHEMBL622907 | 0.81 | AKR1C1 (0.62) | PKMFBP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |