Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.56 |
| ▸ | AR | P10275 | 4/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272363 | 0.90 | PGR (0.61) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3985298 | 0.88 | PGR (0.71) | PGRNR3C2ARNR3C1 | |
| SCHEMBL4285133 | 0.87 | PGR (1.00) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3984979 | 0.85 | PGR (0.76) | PGRNR3C2ARNR3C1 | |
| SCHEMBL6276938 | 0.82 | PGR (0.63) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3984645 | 0.78 | PGR (0.58) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3988412 | 0.77 | PGR (0.78) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3986855 | 0.77 | PGR (0.64) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3987066 | 0.77 | PGR (1.00) | PGRNR3C2ARNR3C1 | |
| SCHEMBL3990556 | 0.77 | PGR (0.66) | PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |