Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363474 | 0.81 | LTB4R2 (0.44) | LTB4R2 | |
| SCHEMBL6254007 | 0.79 | LTB4R2 (0.42) | LTB4R2RARBAGTR1 | |
| SCHEMBL5358339 | 0.78 | LTB4R2 (0.44) | LTB4R2RARB | |
| SCHEMBL6279162 | 0.78 | ALDH1A1 (0.37) | RARBCLCN2PTGS2 | |
| SCHEMBL5360863 | 0.77 | AOC3 (0.48) | LTB4R2 | |
| SCHEMBL5355948 | 0.76 | AOC3 (0.49) | LTB4R2 | |
| SCHEMBL4972529 | 0.75 | PTGER1 (0.43) | LTB4R2BCHEACHE | |
| SCHEMBL5361008 | 0.74 | AOC3 (0.47) | LTB4R2 | |
| SCHEMBL5371478 | 0.73 | LTB4R2 (0.49) | LTB4R2AGTR1 | |
| SCHEMBL5367291 | 0.72 | AOC3 (0.49) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | disclosed |