Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420286 | 1.00 | FKBP1A (0.48) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5420291 | 1.00 | FKBP1A (0.48) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5955017 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5418488 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5954939 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5954946 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5954943 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5955015 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5418489 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 | |
| SCHEMBL5955020 | 0.89 | FKBP1A (0.46) | FKBP1AMEN1KMT2APOLBMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515726-A1 | MORPHOLINE AND TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004002491-A1 | MORPHOLINE AND TETRAHYDROPYRAN DRIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2004-01-08 | — | — | WO | disclosed |