Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 20/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501925 | 0.80 | EPHX2 (0.44) | — | |
| SCHEMBL24090522 | 0.79 | AR (0.40) | F12 | |
| SCHEMBL13059131 | 0.79 | AR (0.40) | F12 | |
| SCHEMBL18886131 | 0.79 | AR (0.40) | F12 | |
| SCHEMBL19457862 | 0.77 | F12 (0.37) | F12F2 | |
| SCHEMBL17075166 | 0.76 | KDM1A (0.34) | F12 | |
| SCHEMBL22050033 | 0.76 | KDM1A (0.34) | F12 | |
| SCHEMBL22050044 | 0.76 | KDM1A (0.34) | F12 | |
| SCHEMBL15882481 | 0.74 | TRPM8 (0.44) | — | |
| SCHEMBL17335654 | 0.74 | TRPM8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556047-A2 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004032848-A2 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |