Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.53 |
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | PROC | P04070 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281026 | 0.86 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL6281885 | 0.85 | F10 (0.55) | F10PRSS1F2PLGPROC | |
| SCHEMBL7393675 | 0.84 | F10 (0.54) | F10PRSS1F2PLGPROC | |
| SCHEMBL7114584 | 0.84 | F10 (0.62) | F10PRSS1F2PLGPROC | |
| SCHEMBL6275986 | 0.83 | F10 (0.61) | F10PRSS1F2PLGPROC | |
| SCHEMBL7119675 | 0.82 | F10 (0.52) | F10PRSS1F2PLGPROC | |
| SCHEMBL6284137 | 0.81 | F10 (0.50) | F10PRSS1F2PLGPROC | |
| SCHEMBL6279410 | 0.80 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL6275757 | 0.80 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL6285012 | 0.80 | F10 (0.53) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | claimed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |