Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284139 | 0.86 | LMNA (0.47) | LMNAEPHX1HDAC7HDAC8HDAC6 | |
| SCHEMBL3229211 | 0.81 | LMNA (0.50) | LMNAHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL3229217 | 0.81 | LMNA (0.50) | LMNAHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL6283999 | 0.81 | EPHX1 (0.50) | LMNAEPHX1 | |
| SCHEMBL6284513 | 0.81 | HSD17B10 (0.31) | EPHX1 | |
| SCHEMBL6290124 | 0.80 | LMNA (0.48) | LMNAHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL6290105 | 0.78 | EPHX2 (0.30) | — | |
| SCHEMBL6286832 | 0.78 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL442584 | 0.76 | LMNA (0.44) | LMNA | |
| SCHEMBL444764 | 0.76 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |