Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518907 | 0.88 | PPARA (0.34) | PPARAKDM4E | |
| SCHEMBL6511266 | 0.82 | CYP3A4 (0.47) | PPARAKDM4E | |
| SCHEMBL6280858 | 0.76 | KDM4E (0.34) | PPARAHTR2AKDM4E | |
| SCHEMBL6275650 | 0.73 | PPARA (0.37) | PPARAKDM4E | |
| SCHEMBL6275352 | 0.73 | HMGCR (0.39) | PPARA | |
| SCHEMBL6508274 | 0.70 | KDM4E (0.33) | KDM4E | |
| SCHEMBL6511665 | 0.69 | PPARG (0.39) | PPARAKDM4E | |
| SCHEMBL6281431 | 0.69 | PPARA (0.34) | PPARAKDM4E | |
| SCHEMBL6281433 | 0.69 | PPARA (0.34) | PPARAKDM4E | |
| SCHEMBL6284901 | 0.68 | PPARA (0.36) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |