Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511781 | 0.88 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL6509614 | 0.86 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL6511397 | 0.85 | PPARA (0.47) | PPARGPPARA | |
| SCHEMBL6363745 | 0.82 | PPARG (0.37) | PPARGPPARA | |
| SCHEMBL6511105 | 0.82 | CYP3A4 (0.47) | PPARGPPARAHSP90AA1KDM4E | |
| SCHEMBL6508274 | 0.81 | KDM4E (0.33) | PPARGHSP90AA1KDM4ELMNAHPGD | |
| SCHEMBL6518907 | 0.81 | PPARA (0.34) | PPARGPPARAHSP90AA1KDM4ELMNA | |
| SCHEMBL6280567 | 0.78 | RARA (0.37) | PPARGPPARAKDM4EMEN1KMT2A | |
| SCHEMBL6281761 | 0.78 | PPARG (0.39) | PPARGPPARAKDM4E | |
| SCHEMBL6511057 | 0.76 | PPARG (0.31) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |