Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668890 | 0.86 | TLR7 (0.46) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL6053075 | 0.85 | TLR7 (0.44) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL4148512 | 0.83 | LMNA (0.43) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL5669098 | 0.80 | TLR7 (0.44) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL8128122 | 0.79 | TLR7 (0.64) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL8126603 | 0.78 | TLR7 (0.47) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL6053164 | 0.77 | TLR7 (0.46) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL483690 | 0.77 | TLR7 (0.50) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL5669048 | 0.76 | TLR7 (0.49) | TLR7POLBPDE4DLMNAHRH2 | |
| SCHEMBL6053092 | 0.76 | TLR7 (0.44) | TLR7POLBPDE4DLMNAHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003064-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-13 | — | — | WO | disclosed |