Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 1,6-Hexanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.65 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28326314 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| Bicarbonate SCHEMBL28327101 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| 1,6-Hexanediol SCHEMBL29109662 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| 1,6-Hexanediol SCHEMBL28737103 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| 1,6-Hexanediol SCHEMBL28984424 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| 1,5-Pentanediol SCHEMBL575113 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| Bicarbonate SCHEMBL28380298 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| 1,5-Pentanediol SCHEMBL29150346 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| 1,6-Hexanediol SCHEMBL6707356 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA | |
| Bicarbonate SCHEMBL28191659 | 1.00 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 450 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700723-A | Copolymerized low-temperature toughened polyamide and preparation method and application thereof | 东莞市奥能工程塑料有限公司上海分公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113956505-B | Polylactic acid emulsion, and preparation method and application thereof | 海南赛诺实业有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-116041696-A | Multiblock copolymer based on long-chain polyamide and aliphatic polycarbonate and preparation method thereof | 中国五环工程有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-113292698-B | Synthetic method of composite modified cationic waterborne polyurethane primer | 中国科学院山西煤炭化学研究所 | 2022-05-24 | — | — | CN | claimed |
| CN-114479753-A | Single-component moisture curing reaction type power battery tab insulating adhesive and preparation method thereof | 北京高盟新材料股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113956428-A | Novel polyurethane material and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2022-01-21 | — | — | CN | claimed |
| CN-113292698-A | Synthetic method of composite modified cationic waterborne polyurethane primer | 中国科学院山西煤炭化学研究所 | 2021-08-24 | — | — | CN | claimed |
| CN-111072903-B | Preparation method of cationic waterborne polyurethane emulsion | 中国科学院山西煤炭化学研究所 | 2021-04-09 | — | — | CN | claimed |
| CN-111394028-A | Photo-activated delayed thermosetting adhesive and preparation method thereof | 枚林优交(上海)新材料开发有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-111154067-A | Low-viscosity high-peel-strength UV (ultraviolet) curing composite adhesive and preparation method thereof | 江苏景宏新材料科技有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-102020967-B | Preparation method of acrylic ester oligomer modified aqueous polyurethane pressure-sensitive adhesive | UNIV CHANGZHOU | 2013-06-19 | — | — | CN | claimed |
| US-8337487-B2 | Reticulated elastomeric matrices, their manufacture and use in implantable devices | BIOMERIX CORPORATION (US) | 2012-12-25 | — | — | US | claimed |
| CN-102352011-A | Preparation method of aqueous hyperbranched polyurethane | UNIV ANHUI | 2012-02-15 | — | — | CN | claimed |
| CN-102206410-A | Preparation method of high-solid-content aqueous polyurethane for leather | UNIV CHANGZHOU | 2011-10-05 | — | — | CN | claimed |
| CN-102020967-A | Preparation method of acrylic ester oligomer modified aqueous polyurethane pressure-sensitive adhesive | UNIV CHANGZHOU | 2011-04-20 | — | — | CN | claimed |
| CN-101824135-A | Preparation method and application of terminated-type cation water-borne polyurethane color fixing agent | UNIV JIANGSU POLYTECHNIC | 2010-09-08 | — | — | CN | claimed |
| CN-101805438-A | Preparation method and applications of cationic waterborne polyurethane surface sizing agent | UNIV JIANGSU POLYTECHNIC | 2010-08-18 | — | — | CN | claimed |
| CN-101768418-A | Preparation method of attapulgite/aqueous polyurethane compound binder | UNIV JIANGSU POLYTECHNIC | 2010-07-07 | — | — | CN | claimed |
| CN-101701140-A | Preparation method and application in wood processing of water-based polyurethane adhesive | UNIV JIANGSU POLYTECHNIC | 2010-05-05 | — | — | CN | claimed |
| CN-101284980-A | Preparation method of waterborne polyurethane adhesive and application in roads reflecting material | UNIV JIANGSU POLYTECHNIC (CN) | 2008-10-15 | — | — | CN | claimed |