Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7835414 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6283861 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7191911 | 0.79 | — | — | |
| SCHEMBL8024058 | 0.79 | — | — | |
| SCHEMBL6283866 | 0.77 | — | — | |
| SCHEMBL7193525 | 0.77 | — | — | |
| SCHEMBL7835416 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6287308 | 0.71 | HTR2C (0.33) | — | |
| Hydrochloric Acid SCHEMBL7198818 | 0.71 | TNKS2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8662955 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802935-A4 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | UNIV LELAND STANFORD JUNIOR (US) | 1998-09-30 | — | — | EP | claimed |
| EP-0802935-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1997-10-29 | — | — | EP | claimed |
| US-5594080-A | POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS | LELAND STANFORD, JR. UNIVERSITY (US) | 1997-01-14 | — | — | US | claimed |
| WO-1995025757-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1995-09-28 | — | — | WO | claimed |
| US-6960550-B2 | Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2005-11-01 | — | — | US | disclosed |
| US-6566544-B1 | Indene ring-containing metallocene-complex catalysts | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY | 2003-05-20 | — | — | US | disclosed |
| US-6518378-B2 | Using an unbridged cyclopentadienyl metallocene catalyst capable of interconverting between states with different copolymerization characteristics | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2003-02-11 | — | — | US | disclosed |
| US-6479685-B2 | POLYMERIZING ETHYLENE AND ANOTHER ALPHA-OLEFIN IN THE PRESENCE OF AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST COMPONENT AND A CO-CATALYST | THE BOARD OF TRUSTEES OF THE LELAND STANDARD JUNIOR UNIVERSITY | 2002-11-12 | — | — | US | disclosed |
| US-20020115805-A1 | Methods of production of ethylene copolymers having narrow composition distributions and high melting temperatures | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2002-08-22 | — | — | US | disclosed |
| US-6380341-B1 | A COPOLYMER OF ETHYLENE WITH AT LEAST ONE COMONOMER CONTAINING AT LEAST 4 CARBON ATOMS, BEING CHARACTERIZED BY A POLYDISPERSITY GREATER THAN 2, A BROAD MELTING POINT RANGE HAVING MULTIPLE MELTING POINT PEAKS | THE BOARD OF TRUSTEES OF LELAND STANFORD JR. UNIVERSITY | 2002-04-30 | — | — | US | disclosed |
| US-6346580-B1 | COMPOSITION COMPRISING PROPYLENE HOMOPOLYMER HAVING SPECIFIED PHYSICAL PROPERTIES AND PROPYLENE-BASED RESIN WHICH CONSISTS OF PROPYLENE HOMOPOLYMER HAVING ISOTACTIC PENTAD FRACTION OF 0.970 OR MORE AND ETHYLENE-PROPYLENE RANDOM COPOLYMER | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| US-20010049425-A1 | High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis | BP CORPORATION NORTH AMERICA INC. | 2001-12-06 | — | — | US | disclosed |
| US-20010034426-A1 | High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis | BP CORPORATION NORTH AMERICA INC. | 2001-10-25 | — | — | US | disclosed |
| US-6169151-B1 | MADE BY POLYMERIZING ETHYLENE AND ALPHA-OLEFIN(S) USING AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST AND COCATALYST; CRYSTALLIZABLE ELASTOMERIC COPOLYMER PRODUCT HAS HIGHER MELTING POINT, NARROW COMPOSITION DISTRIBUTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2001-01-02 | — | — | US | disclosed |
| US-6160064-A | POLYMERIZING MONOMERS IN PRESENCE OF CATALYST SYSTEM COMPRISING UNBRIDGED FLUXIONAL METALLOCENE AND COCATALYST, INTRODUCING ETHYLENE INTO SYSTEM TO INDUCE POLYMERIZATION RATE ENHANCEMENT/ELASTOMERIC PROPERTY ENHANCING EFFECTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-12-12 | — | — | US | disclosed |
| US-5969070-A | HOMOGENEOUS COMPOSITION FORMED FROM LINEAR OR BRANCHED CHAIN C3 TO C10 MONOMERS SUCH AS PROPYLENE, 1-BUTENE, 1-PENTENE, 4-METHYL-1-PENTENE, 1-HEXENE AND MIXTURES THEREOF, COMPRISING ALTERNATING ISOTACTIC AND ATACTIC DISASTEREOSEQUENCES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1999035171-A1 | HIGH-MELTING POLYOLEFIN COPOLYMER ELASTOMERS, CATALYSTS AND METHODS OF SYNTHESIS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) | 1999-07-15 | — | — | WO | disclosed |
| EP-0802935-A4 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | UNIV LELAND STANFORD JUNIOR (US) | 1998-09-30 | — | — | EP | disclosed |
| EP-0802935-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995025757-A1 | THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1995-09-28 | — | — | WO | disclosed |