Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307858 | 0.85 | HPGD (0.51) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL8523487 | 0.82 | CYP19A1 (0.61) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL9574619 | 0.81 | SMN1; SMN2 (0.60) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL8942347 | 0.80 | MAPT (0.55) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL9561587 | 0.80 | SMN1; SMN2 (0.57) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8942526 | 0.80 | MAPT (0.54) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL8942460 | 0.79 | MAPT (0.56) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| Nimesulide SCHEMBL29393272 | 0.79 | CYP19A1 (1.00) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| Nimesulide SCHEMBL24882 | 0.79 | CYP19A1 (1.00) | CYP19A1PTGS1PTGS2MEN1KMT2A | |
| Nimesulide SCHEMBL4796058 | 0.79 | CYP19A1 (1.00) | CYP19A1PTGS1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6056759-A | — | — | None | — | — | JP | disclosed |
| JP-8127533-A | — | — | None | — | — | JP | disclosed |
| JP-2005247817-A | REMEDY FOR OPHTHALMIC INFLAMMATION AND AQUEOUS SOLUTION CONTAINING 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND | SENJU PHARMACEUT CO LTD | 2005-09-15 | — | — | JP | disclosed |
| EP-0645374-B1 | 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-11-20 | — | — | EP | disclosed |
| JP-H08127533-A | COMPOSITION FOR ORAL SOLID PHARMACEUTICAL PREPARATION | TAISHO PHARMACEUT CO LTD | 1996-05-21 | — | — | JP | disclosed |
| US-5449826-A | Antiinflammatory, antipyretic, antirheumatic, and analgesic agents | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0645374-A1 | 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-29 | — | — | EP | disclosed |
| JP-H0656759-A | 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND | TAISHO PHARMACEUT CO LTD | 1994-03-01 | — | — | JP | disclosed |