Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281034 | 0.85 | CYP19A1 (0.65) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL8942422 | 0.81 | HPGD (0.45) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL11819011 | 0.78 | HPGD (0.65) | HPGDPIN1TBXA2RMEN1KMT2A | |
| Butylamine SCHEMBL8942217 | 0.77 | TBXA2R (0.45) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL8942530 | 0.75 | KDM4E (0.47) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL8942212 | 0.75 | TBXA2R (0.45) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL9233845 | 0.75 | PTGS1 (0.40) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL9528388 | 0.73 | HSPB1 (0.46) | HPGDPTGS1PTGS2PIN1TBXA2R | |
| SCHEMBL11186476 | 0.72 | PTGS2 (0.55) | HPGDPTGS1PTGS2TBXA2RMEN1 | |
| SCHEMBL8525177 | 0.72 | PTGS1 (0.50) | HPGDPTGS1PTGS2PIN1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6072988-A | — | — | None | — | — | JP | disclosed |
| JP-H0672988-A | 5-AMINO-2-HALOPHENOXYSULFONANILIDE COMPOUND | TAISHO PHARMACEUT CO LTD | 1994-03-15 | — | — | JP | disclosed |