4,8-Dihydroxy-1-Tetralone

4,8-Dihydroxy-1-Tetralone

SCHEMBL6281138

O=C1CC[C@H](O)c2cccc(O)c21

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLL Q9UGP5 1/20 0.62
ELAVL1 Q15717 1/20 0.41
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
ALOX15 P16050 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 2/20 0.39
USP2 O75604 2/20 0.39
CYP3A4 P08684 2/20 0.39
THRB P10828 2/20 0.39
KMT2A Q03164 2/20 0.39
HPN P05981 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
KDR P35968 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4,8-Dihydroxy-1-Tetralone SCHEMBL30966482 1.00 POLL (0.62) POLLELAVL1ALDH1A1MAPTALOX15
4,8-Dihydroxy-1-Tetralone SCHEMBL27988260 1.00 POLL (0.62) POLLELAVL1ALDH1A1MAPTALOX15
SCHEMBL23691943 0.82 POLL (0.45) POLLELAVL1ALDH1A1MAPTALOX15
SCHEMBL30224133 0.82 POLL (0.45) POLLELAVL1ALDH1A1MAPTALOX15
SCHEMBL23691930 0.82 POLL (0.45) POLLELAVL1ALDH1A1MAPTALOX15
SCHEMBL30224129 0.82 POLL (0.45) POLLELAVL1ALDH1A1MAPTALOX15
Nodulisporone SCHEMBL29991198 0.77 POLL (1.00) POLLELAVL1ALDH1A1MAPTHSD17B10
SCHEMBL28350939 0.74 POLL (0.41) POLLELAVL1MAPTMEN1KMT2A
SCHEMBL9534010 0.73 ESR1 (0.51) CYP3A4
SCHEMBL13518633 0.73 ESR1 (0.51) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005206529-A NAPHTHALENE COMPOUND AND APPLICATION THEREOF FOR CONTROLLING PLANT DISEASE SUMITOMO CHEMICAL CO LTD 2005-08-04 JP disclosed
JP-2005206530-A AGENT FOR CONTROLLING PLANT DISEASE CAUSED BY DOWNY MILDEW OR LATE BLIGHT SUMITOMO CHEMICAL CO LTD 2005-08-04 JP disclosed