SCHEMBL30224129

SCHEMBL30224129

O=C1CC[C@H](c2ccc(O)c3c2C(=O)CC[C@@H]3O)c2cccc(O)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLL Q9UGP5 1/20 0.45
ELAVL1 Q15717 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPN P05981 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
PTGS1 P23219 1/20 0.32
PDE4A P27815 1/20 0.32
KDR P35968 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SIRT5 Q9NXA8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23691930 1.00 POLL (0.45) POLLELAVL1MEN1KMT2AUSP2
SCHEMBL23691943 1.00 POLL (0.45) POLLELAVL1MEN1KMT2AUSP2
SCHEMBL30224133 1.00 POLL (0.45) POLLELAVL1MEN1KMT2AUSP2
SCHEMBL23691931 0.84 TERT (0.37) POLLCLK2PTGS2MAOA
SCHEMBL23692131 0.84 TERT (0.37) POLLCLK2PTGS2MAOA
SCHEMBL30224128 0.84 TERT (0.37) POLLCLK2PTGS2MAOA
4,8-Dihydroxy-1-Tetralone SCHEMBL30966482 0.82 POLL (0.62) POLLELAVL1MEN1KMT2AUSP2
4,8-Dihydroxy-1-Tetralone SCHEMBL6281138 0.82 POLL (0.62) POLLELAVL1MEN1KMT2AUSP2
4,8-Dihydroxy-1-Tetralone SCHEMBL27988260 0.82 POLL (0.62) POLLELAVL1MEN1KMT2AUSP2
SCHEMBL13744539 0.79 CLK2 (0.43) POLLMEN1KMT2AUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230102379-A1 CITRUS HUANGLONGBING THERAPEUTIC COMPOUNDS POINT LOMA NAZARENE UNIVERSITY 2023-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230102379-A1 CITRUS HUANGLONGBING THERAPEUTIC COMPOUNDS LSS, REL, RPN1 POLL 4125/4885ELAVL1 27/4885MEN1 3542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.