SCHEMBL6281528

SCHEMBL6281528

C=Cc1ccc(C(C)C(C)c2ccc(C=C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
TSHR P16473 1/20 0.43
HDAC8 Q9BY41 2/20 0.42
TYR P14679 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
PTGS2 P35354 3/20 0.36
TP53 P04637 1/20 0.34
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
TRPA1 O75762 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21306480 0.90 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL367595 0.84 TYR (0.58) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL1140933 0.84 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL1647492 0.84 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TYRTDP1
Methane SCHEMBL11025053 0.82 TYR (0.56) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL394726 0.82 ALDH1A1 (0.55) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL8674704 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL9771232 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL9652787 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL9772098 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TYRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855952-B2 Semiconductor device and semiconductor package HITACHI, LTD. (JP) 2005-02-15 US disclosed
US-20040038021-A1 Semiconductor device and semiconductor package HITACHI, LTD. (JP) 2004-02-26 US disclosed