P-Xylene

P-Xylene

SCHEMBL6281558

Cc1ccc(C)cc1.O=C(O)CCc1cccnc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 12/20 0.68
NAPRT Q6XQN6 1/20 0.57
FFAR1 O14842 2/20 0.55
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KEAP1 Q14145 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333061 0.92 TBXAS1 (0.78) TBXAS1NAPRTFFAR1CYP1A2CYP3A4
SCHEMBL29403620 0.92 TBXAS1 (0.78) TBXAS1NAPRTFFAR1CYP1A2CYP3A4
SCHEMBL27446829 0.90 TBXAS1 (0.76) TBXAS1NAPRTFFAR1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL305976 0.90 TBXAS1 (0.79) TBXAS1NAPRTFFAR1CYP1A2CYP3A4
O-Xylene SCHEMBL6281561 0.89 TBXAS1 (0.66) TBXAS1NAPRTFFAR1CYP1A2CYP3A4
Trifluoroacetic Acid SCHEMBL27502761 0.84 TBXAS1 (0.68) TBXAS1NAPRTFFAR1CYP1A2CYP3A4
SCHEMBL15316698 0.83 TDP1 (0.68) TBXAS1NAPRTCYP1A2CYP3A4CYP2C9
SCHEMBL1583762 0.81 TBXAS1 (0.90) TBXAS1NAPRT
SCHEMBL30612524 0.81 TBXAS1 (0.90) TBXAS1NAPRT
SCHEMBL9706562 0.81 NAMPT (0.67) CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005115148-A1 3-ARYL-3-HYDROXY-2-METHYLENEPROPIONIC ACID ESTERS AS FUNGICIDES CROPSOLUTION, INC. (US) 2005-12-08 WO disclosed