Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81370 | 0.84 | TYMS (0.69) | TYMSLPAR3LPAR2ALDH1A1BBOX1 | |
| SCHEMBL8352725 | 0.84 | TYMS (0.69) | TYMSLPAR3LPAR2ALDH1A1BBOX1 | |
| Ethylamine SCHEMBL11312343 | 0.83 | ALDH1A1 (0.61) | TYMSLPAR3LPAR2ALDH1A1BBOX1 | |
| Ethephon SCHEMBL28762926 | 0.82 | TYMS (0.50) | TYMSLPAR3LPAR2ALDH1A1BTN3A1 | |
| Ethylene Glycol SCHEMBL15452842 | 0.81 | TYMS (0.56) | TYMSLPAR3LPAR2ALDH1A1BTN3A1 | |
| Methylamine SCHEMBL10871952 | 0.81 | ALDH1A1 (0.59) | TYMSLPAR3LPAR2ALDH1A1BBOX1 | |
| Ethylene Glycol SCHEMBL15452885 | 0.81 | TYMS (0.56) | TYMSLPAR3LPAR2ALDH1A1BTN3A1 | |
| Ethylene Glycol SCHEMBL1682708 | 0.81 | TYMS (0.56) | TYMSLPAR3LPAR2ALDH1A1BTN3A1 | |
| Ethylene Glycol SCHEMBL15452872 | 0.81 | TYMS (0.56) | TYMSLPAR3LPAR2ALDH1A1BTN3A1 | |
| Phosphoric Acid SCHEMBL173991 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414666-B2 | Surface-modified cyanide-based transition metal compounds | NATRON ENERGY, INC. (US) | 2019-09-17 | — | — | US | claimed |
| EP-3475403-A1 | IMPROVED REMOVAL OF HYDROPHILIC BODY SOILS | The Procter and Gamble Company (US) | 2019-05-01 | — | — | EP | claimed |
| EP-3331827-A1 | SURFACE-MODIFIED CYANIDE-BASED TRANSITION METAL COMPOUNDS | Natron Energy, Inc. (US) | 2018-06-13 | — | — | EP | claimed |
| US-20180105432-A1 | SURFACE-MODIFIED CYANIDE-BASED TRANSITION METAL COMPOUNDS | NATRON ENERGY, INC. (US) | 2018-04-19 | — | — | US | claimed |
| WO-2018005457-A1 | IMPROVED REMOVAL OF HYDROPHILIC BODY SOILS | THE PROCTER & GAMBLE COMPANY (US) | 2018-01-04 | — | — | WO | claimed |
| US-20170369819-A1 | REMOVAL OF HYDROPHILIC BODY SOILS | THE PROCTER & GAMBLE COMPANY | 2017-12-28 | — | — | US | claimed |
| EP-2295531-B1 | A FLUID LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2017-02-22 | — | — | EP | claimed |
| US-9550964-B2 | Detergent compositions containing pyridinol-N-oxide compositions | THE PROCTER & GAMBLE COMPANY (US) | 2017-01-24 | — | — | US | claimed |
| WO-2017004272-A1 | SURFACE-MODIFIED CYANIDE-BASED TRANSITION METAL COMPOUNDS | Alveo Energy, Inc. (US) | 2017-01-05 | — | — | WO | claimed |
| US-20160293932-A1 | SYNTHETIC METHODS FOR TRANSITION METAL COORDINATION COMPOUNDS | Alveo Energy, Inc. (US) | 2016-10-06 | — | — | US | claimed |
| US-9299981-B1 | Surface-modified cyanide-based transition metal compounds | Alveo Energy, Inc. (US) | 2016-03-29 | — | — | US | claimed |
| US-20150105311-A1 | FLUID LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2015-04-16 | — | — | US | claimed |
| US-20140357541-A1 | DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOSITIONS | PROCTER & GAMBLE (US) | 2014-12-04 | — | — | US | claimed |
| WO-2011031712-A2 | A FLUID LAUNDRY DETERGENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2011-03-17 | — | — | WO | claimed |
| US-20110065624-A1 | FLUID LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE COMPANY, THE | 2011-03-17 | — | — | US | claimed |
| EP-2295531-A1 | A fluid laundry detergent composition | The Procter & Gamble Company (US) | 2011-03-16 | — | — | EP | claimed |
| EP-0799887-B1 | Fabric softener compositions | PROCTER & GAMBLE (US) | 2003-06-11 | — | — | EP | claimed |
| US-6020304-A | Fabric softener compositions | THE PROCTER & GAMBLE COMPANY (US) | 2000-02-01 | — | — | US | claimed |
| WO-1997036981-A1 | FABRIC SOFTENER COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0799887-A1 | Fabric softener compositions | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-08 | — | — | EP | claimed |