Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252263 | 0.86 | DHODH (0.45) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL6281715 | 0.82 | KDM4E (0.32) | KDM4EPOLBL3MBTL1DHODH | |
| SCHEMBL28247062 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL12491709 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL5415654 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL12491707 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL17024327 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL17024326 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| SCHEMBL217840 | 0.80 | DHODH (0.41) | DHODHPARP1PARP15PARP10FABP4 | |
| Bromide SCHEMBL689744 | 0.77 | DHODH (0.39) | DHODHPARP1PARP15PARP10FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123913-A2 | REVERSIBLY MODIFIED THERMOSTABLE ENZYME COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | NUSTAR LABORATORY (US) | 2005-12-29 | — | — | WO | disclosed |