Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281708 | 0.82 | KDM4E (0.41) | KDM4EPOLBL3MBTL1DHODH | |
| SCHEMBL252316 | 0.80 | DHODH (0.38) | DHODH | |
| SCHEMBL1207568 | 0.76 | SLC6A2 (0.37) | DHODH | |
| SCHEMBL2646143 | 0.76 | SLC6A2 (0.37) | DHODH | |
| SCHEMBL9753632 | 0.72 | ELANE (0.36) | — | |
| SCHEMBL252263 | 0.71 | DHODH (0.45) | DHODH | |
| SCHEMBL9561660 | 0.69 | SLC6A3 (0.50) | DHODH | |
| SCHEMBL15400430 | 0.68 | POLB (0.35) | KDM4EPOLB | |
| SCHEMBL4344019 | 0.68 | POLB (0.35) | KDM4EPOLB | |
| SCHEMBL17024326 | 0.66 | DHODH (0.41) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123913-A2 | REVERSIBLY MODIFIED THERMOSTABLE ENZYME COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | NUSTAR LABORATORY (US) | 2005-12-29 | — | — | WO | disclosed |