Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722438 | 0.88 | IDO1 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9592829 | 0.83 | IDO1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2APKM | |
| SCHEMBL9440363 | 0.81 | IDO1 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2APKM | |
| SCHEMBL8684287 | 0.81 | MEN1 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8684282 | 0.81 | IDO1 (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4768171 | 0.80 | IDO1 (0.44) | SMN1; SMN2MEN1KMT2AMAPTIDO1 | |
| SCHEMBL3295742 | 0.80 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AMAPTIDO1 | |
| SCHEMBL2097653 | 0.79 | IDO1 (0.65) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL27607304 | 0.78 | MEN1 (0.59) | SMN1; SMN2MEN1KMT2AMAPTIDO1 | |
| SCHEMBL21186285 | 0.78 | CYP3A4 (0.45) | ALDH1A1MEN1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |