Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31175762 | 0.85 | CYP3A4 (0.52) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL990234 | 0.85 | CYP3A4 (0.52) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL8765756 | 0.83 | CYP3A4 (0.56) | CYP3A4ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL1149063 | 0.78 | MAPT (0.49) | CYP3A4ALDH1A1TSHRTDP1MEN1 | |
| SCHEMBL6282006 | 0.78 | SMN1; SMN2 (0.52) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8217107 | 0.77 | MPO (0.44) | CYP3A4ALDH1A1TSHRTDP1MAOB | |
| SCHEMBL9629297 | 0.77 | CYP3A4 (0.52) | CYP3A4ALDH1A1TSHRTDP1MAOB | |
| SCHEMBL9440363 | 0.75 | IDO1 (0.46) | ALDH1A1MEN1MAPTKMT2AADCY10 | |
| SCHEMBL5368754 | 0.75 | ALOX15 (0.56) | CYP3A4ALDH1A1ALOX15CRHBPCRHR2 | |
| SCHEMBL5921916 | 0.75 | RAB9A (0.56) | ALDH1A1ALOX15HSD17B10MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924169-A | Dihydroquinoline derivative and pharmaceutical application thereof in resisting influenza | 山东大学齐鲁医院 | 2024-04-26 | — | — | CN | disclosed |
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |