Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282024 | 0.89 | RAB9A (0.58) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6262169 | 0.87 | RAB9A (0.58) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6264952 | 0.84 | CNR1 (0.53) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3919375 | 0.83 | PTPN1 (0.54) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6262178 | 0.81 | RAB9A (0.58) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6272106 | 0.77 | HPGD (0.55) | RAB9ANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL3914078 | 0.76 | PTPN1 (0.55) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3905459 | 0.75 | PTPN1 (0.70) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3906506 | 0.75 | PTPN1 (0.58) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6264957 | 0.72 | CNR1 (0.53) | RAB9ANPC1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |