SCHEMBL6282061

SCHEMBL6282061

OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1ccc(SSc2ccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)C(F)(F)F)cc2)cc1)C(F)(F)F

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8273662 0.93 CETP (0.77) CETP
SCHEMBL7679579 0.90 CETP (0.72) CETP
SCHEMBL5178733 0.89 CETP (0.69) CETP
SCHEMBL993489 0.86 CETP (0.94) CETP
SCHEMBL992448 0.86 CETP (0.94) CETP
SCHEMBL3278131 0.86 CETP (0.80) CETP
SCHEMBL5179676 0.86 CETP (0.80) CETP
SCHEMBL3278134 0.86 CETP (0.80) CETP
SCHEMBL14528287 0.85 CETP (0.92) CETP
SCHEMBL5178754 0.85 CETP (0.78) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005117869-A1 COMBINATIONS COMPRISING (S)-AMLODIPINE AND A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR, AND METHODS FOR REDUCING HYPERTENSION SEPRACOR INC. (US) 2005-12-15 WO disclosed