Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179946 | 0.93 | CETP (0.74) | CETP | |
| SCHEMBL6282061 | 0.90 | CETP (0.75) | CETP | |
| SCHEMBL5178733 | 0.87 | CETP (0.69) | CETP | |
| SCHEMBL7649062 | 0.85 | CETP (0.70) | CETP | |
| SCHEMBL8273662 | 0.85 | CETP (0.77) | CETP | |
| SCHEMBL7679574 | 0.84 | CETP (0.64) | CETP | |
| SCHEMBL6136874 | 0.84 | CETP (1.00) | CETP | |
| SCHEMBL13385246 | 0.83 | CETP (0.88) | CETP | |
| SCHEMBL14528287 | 0.83 | CETP (0.92) | CETP | |
| SCHEMBL5179676 | 0.82 | CETP (0.80) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458803-B1 | COMPOSITIONS AND METHODS FOR TREATING ATHEROSCLEROSIS AND OTHER CORONARY ARTERY DISEASES. PREFERRED TERTIARY-HETEROALKYLAMINE COMPOUNDS ARE SUBSTITUTED N-PHENYL-N-HETEROARALKYL AMINOALCOHOLS. A PREFERRED SPECIFIC | G.D. SEARLE & CO. | 2002-10-01 | — | — | US | disclosed |