⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906814 | 1.00 | — | — | |
| SCHEMBL8370948 | 1.00 | — | — | |
| SCHEMBL11442823 | 0.79 | KDM4E (0.70) | — | |
| SCHEMBL11442824 | 0.79 | KDM4E (0.70) | — | |
| SCHEMBL11442822 | 0.79 | KDM4E (0.70) | — | |
| SCHEMBL30499040 | 0.79 | KDM4E (0.70) | — | |
| SCHEMBL1703735 | 0.79 | — | — | |
| SCHEMBL1703734 | 0.79 | — | — | |
| SCHEMBL648808 | 0.78 | — | — | |
| SCHEMBL8372870 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002313-A1 | [11C]-LABELED ACYCLIC RETINOID, CENTRAL NERVOUS SYSTEM ACTIVATOR, AND PRODUCTION METHODS FOR SAME | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2024-01-04 | — | — | US | disclosed |
| EP-4249058-A1 | [11C]-LABELLED ACYCLIC RETINOID, CENTRAL NERVOUS SYSTEM ACTIVATOR, AND PRODUCTION METHODS FOR SAME | National Center for Geriatrics and Gerontology (JP) | 2023-09-27 | — | — | EP | disclosed |
| EP-3981766-A1 | INDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Eisai R&D Management Co., Ltd. (JP) | 2022-04-13 | — | — | EP | disclosed |
| CN-113024466-A | Tetra-substituted olefin compound and use thereof | 卫材 R&D 管理有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-107847498-B | Tetra-substituted olefin compound and use thereof | 卫材R&D管理有限公司 | 2021-04-13 | — | — | CN | disclosed |
| US-10919835-B2 | Compounds and synthetic methods for the preparation of retinoid X receptor-specific retinoids | Io Therapeutics, Inc. (US) | 2021-02-16 | — | — | US | disclosed |
| US-10851065-B2 | Tetrasubstituted alkene compounds and their use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20200190008-A1 | COMPOUNDS AND SYNTHETIC METHODS FOR THE PREPARATION OF RETINOID X RECEPTOR-SPECIFIC RETINOIDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-06-18 | — | — | US | disclosed |
| CN-108026088-A | Oxadiazole derivatives as HDAC inhibitors | 武田药品工业株式会社 | 2018-05-11 | — | — | CN | disclosed |
| US-20180127378-A1 | TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-05-10 | — | — | US | disclosed |
| US-4537720-A | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamino)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0109816-A1 | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4444621-A | Process and apparatus for the deresination and brightness improvement of cellulose pulp | MO OCH DOMSJO AKTIEBOLAG (SE) | 1984-04-24 | — | — | US | disclosed |
| US-4436596-A | N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1984-03-13 | — | — | US | disclosed |
| US-4372811-A | INHIBITION OF DEGRADATION OF CARBOHYDRATES | MO OCH DOMSJO AKTIEBOLAG (SE) | 1983-02-08 | — | — | US | disclosed |
| US-4244778-A | BLEACHING IN A SHORT PROCESSING TIME | MODO-CHEMETICS AB (SE) | 1981-01-13 | — | — | US | disclosed |
| US-4222819-A | COMPLEXING AGENT TO INHIBIT ATTACK ON CELLULOSE, DELIGNIFICATION | MO OCH DOMSJO AKTIEBOLAG (SE) | 1980-09-16 | — | — | US | disclosed |
| US-4087318-A | Oxygen-alkali delignification of lignocellulosic material in the presence of a manganese compound | MO OCH DOMSJO AKTIEBOLAG (SW) | 1978-05-02 | — | — | US | disclosed |
| US-4050981-A | Process for the delignification of lignocellulosic material by maintaining a concentration of carbon monoxide in the presence of oxygen and alkali | MO OCH DOMSJO AKTIEBOLAG (SW) | 1977-09-27 | — | — | US | disclosed |
| US-4016029-A | CONTACTING WITH OXYGEN AND SODIUM BICARBONATE, REMOVING CARBON DIOXIDE | MO OCH DOMSJO AKTIEBOLAG (SW) | 1977-04-05 | — | — | US | disclosed |