Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282211 | 1.00 | SRC (0.37) | SRCBRD4ELANEMAPTALDH1A1 | |
| SCHEMBL5952166 | 0.92 | BRD4 (0.37) | SRCBRD4ELANEMAPTALDH1A1 | |
| SCHEMBL5952161 | 0.92 | BRD4 (0.37) | SRCBRD4ELANEMAPTALDH1A1 | |
| SCHEMBL5953089 | 0.85 | MAPT (0.38) | SRCBRD4ELANEMAPTALDH1A1 | |
| SCHEMBL10126744 | 0.84 | L3MBTL1 (0.46) | ELANENPC1RAB9ACA12CA1 | |
| SCHEMBL5952034 | 0.81 | PDE4B (0.40) | BRD4ELANEMAPTALDH1A1PDE4B | |
| SCHEMBL5952029 | 0.81 | PDE4B (0.40) | BRD4ELANEMAPTALDH1A1PDE4B | |
| SCHEMBL5952979 | 0.79 | MAPT (0.39) | SRCBRD4ELANEMAPTALDH1A1 | |
| SCHEMBL15149187 | 0.75 | NPC1 (0.38) | ELANEMAPTALDH1A1TTRDPP4 | |
| SCHEMBL28266630 | 0.73 | LSS (0.37) | BRD4ELANEHPGDMAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897208-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-24 | — | — | US | disclosed |