Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 17/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628252 | 1.00 | MKNK1 (0.57) | MKNK1FYNPIM1VNN1 | |
| SCHEMBL2257059 | 0.94 | MKNK1 (0.63) | MKNK1FYNPIM1 | |
| SCHEMBL627314 | 0.84 | MKNK1 (0.53) | MKNK1FYNPIM1VNN1 | |
| SCHEMBL624132 | 0.79 | MKNK1 (0.48) | MKNK1FYN | |
| SCHEMBL627066 | 0.78 | KDM4E (0.46) | MKNK1FYN | |
| SCHEMBL15324842 | 0.77 | MKNK1 (0.59) | MKNK1FYNPIM1 | |
| SCHEMBL1944317 | 0.75 | MKNK1 (0.78) | MKNK1FYNPIM1 | |
| SCHEMBL628253 | 0.75 | MKNK1 (0.40) | MKNK1FYNPIM1VNN1 | |
| SCHEMBL1944246 | 0.73 | MKNK1 (0.80) | MKNK1FYNPIM1 | |
| SCHEMBL1945274 | 0.73 | MKNK1 (0.74) | MKNK1FYNPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |