Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279824 | 0.96 | CNR2 (0.43) | CNR2HTR2AKCNH2 | |
| SCHEMBL20161341 | 0.92 | MAPT (0.43) | CNR2HTR2A | |
| SCHEMBL1815516 | 0.86 | CNR2 (0.46) | CNR2KCNH2 | |
| SCHEMBL12677177 | 0.86 | CNR2 (0.46) | CNR2KCNH2 | |
| SCHEMBL29138370 | 0.85 | CNR2 (0.48) | CNR2KCNH2 | |
| SCHEMBL29138376 | 0.85 | CNR2 (0.48) | CNR2KCNH2 | |
| SCHEMBL29138372 | 0.85 | CNR2 (0.48) | CNR2KCNH2 | |
| SCHEMBL29138379 | 0.85 | CNR2 (0.48) | CNR2KCNH2 | |
| SCHEMBL29138371 | 0.85 | CNR2 (0.48) | CNR2KCNH2 | |
| SCHEMBL29138336 | 0.85 | CNR2 (0.48) | CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | CNR2 3009/4885HTR2A 4225/4885KCNH2 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.