Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282799 | 0.92 | CNR2 (0.46) | CNR2HTR2A | |
| SCHEMBL6279824 | 0.89 | CNR2 (0.43) | CNR2HTR2A | |
| SCHEMBL20161128 | 0.88 | S1PR1 (0.43) | EGFRERBB2CNR2HRH3PSIP1 | |
| SCHEMBL7153351 | 0.85 | EGFR (0.50) | MAPTNR1H2NR1H3EGFRERBB2 | |
| SCHEMBL11803623 | 0.83 | NR1H2 (0.44) | MAPTNR1H2NR1H3EGFRERBB2 | |
| SCHEMBL2491668 | 0.83 | ALDH1A1 (0.48) | MAPTNR1H2NR1H3EGFRERBB2 | |
| SCHEMBL7932826 | 0.82 | CA2 (0.47) | MAPTEGFRERBB2CHRM2CHRM5 | |
| SCHEMBL768272 | 0.81 | EGFR (0.47) | MAPTNR1H2NR1H3EGFRERBB2 | |
| SCHEMBL2014159 | 0.81 | EGFR (0.47) | MAPTNR1H2NR1H3EGFRERBB2 | |
| SCHEMBL17663681 | 0.81 | EGFR (0.47) | MAPTNR1H2NR1H3EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10487076-B2 | Compositions and methods for treating diseases and conditions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-11-26 | — | — | US | disclosed |
| US-20180134693-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND CONDITIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10487076-B2 | Compositions and methods for treating diseases and conditions | C1S, SLC10A1, C1R | MAPT 2871/4885NR1H2 143/4885NR1H3 95/4885 |
| US-20180134693-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND CONDITIONS | C1S, SLC10A1, C1R | MAPT 2871/4885NR1H2 143/4885NR1H3 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.