Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 10/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7857894 | 0.98 | TAAR1 (0.52) | TAAR1KCNN4KIF11CYP1A2CYP3A4 | |
| SCHEMBL2170468 | 0.85 | KCNN4 (0.48) | TAAR1KCNN4CYP1A2CYP3A4 | |
| SCHEMBL22609038 | 0.85 | TAAR1 (0.56) | TAAR1KCNN4KIF11 | |
| SCHEMBL27649423 | 0.82 | KCNN4 (0.46) | TAAR1KCNN4CYP1A2CYP3A4 | |
| SCHEMBL11645253 | 0.80 | SIGMAR1 (0.47) | TAAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL51317 | 0.79 | TAAR1 (0.47) | TAAR1KCNN4KIF11CYP3A4CYP2D6 | |
| SCHEMBL16892586 | 0.77 | TAAR1 (0.31) | TAAR1 | |
| Hydrochloric Acid SCHEMBL11650778 | 0.77 | TAAR1 (0.45) | TAAR1KCNN4KIF11CYP3A4CYP2D6 | |
| SCHEMBL6620290 | 0.77 | TSHR (0.48) | TAAR1KIF11CYP3A4 | |
| SCHEMBL13672218 | 0.77 | TAAR1 (0.38) | TAAR1KIF11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878753-B1 | Process for producing polyurethane foam | KAO CORPORATION (JP) | 2005-04-12 | — | — | US | disclosed |
| US-6001860-A | N-aryl and N-heteroarylurea derivatives as inhibitors of acyl coenzyme A: Cholesterol acyl transferase (ACAT) | PFIZER INC. (US) | 1999-12-14 | — | — | US | disclosed |
| US-5886183-A | Naphthalenelactamimide fluorescence dyes | CIBA SPECIALTY CHEMICALS CORPORATOIN | 1999-03-23 | — | — | US | disclosed |
| EP-0769532-A1 | Naphtholactamimide fluorescent dyes | Ciba SC Holding AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| EP-0642498-A1 | NEW $i(N)-ARYL AND $i(N)-HETEROARYLUREA DERIVATIVES AS INHIBITORS OF ACYL COENZYME A:CHOLESTEROL ACYL TRANSFERASE (ACAT) | PFIZER INC. (US) | 1995-03-15 | — | — | EP | disclosed |
| CN-1080919-A | As ACAT inhibitors, new N-aryl and N-heteroaryl-ureas analog derivative | PFIZER (US) | 1994-01-19 | — | — | CN | disclosed |
| WO-1993024458-A1 | NEW N-ARYL AND N-HETEROARYLUREA DERIVATIVES AS INHIBITORS OF ACYL COENZYME A:CHOLESTEROL ACYL TRANSFERASE (ACAT) | PFIZER INC. (US) | 1993-12-09 | — | — | WO | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |