Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.72 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.72 |
| ▸ | F2 | P00734 | 9/20 | 0.72 |
| ▸ | PLG | P00747 | 5/20 | 0.60 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281882 | 0.91 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6279956 | 0.86 | F10 (0.55) | F10PRSS1F2PLGPROC | |
| SCHEMBL6295248 | 0.84 | F10 (0.54) | F10PRSS1F2PLGPROC | |
| SCHEMBL7119767 | 0.84 | F10 (1.00) | F10PRSS1F2PLGPROC | |
| SCHEMBL7126671 | 0.82 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6283268 | 0.82 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6281579 | 0.82 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6278829 | 0.82 | F10 (0.52) | F10PRSS1F2PLGPROC | |
| SCHEMBL6277852 | 0.81 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6279004 | 0.80 | F10 (0.53) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |