Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.70 |
| ▸ | F2 | P00734 | 9/20 | 0.70 |
| ▸ | PLG | P00747 | 5/20 | 0.70 |
| ▸ | PROC | P04070 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283170 | 0.91 | F10 (0.72) | F10PRSS1F2PLGPROC | |
| SCHEMBL6279956 | 0.88 | F10 (0.55) | F10PRSS1F2PLGPROC | |
| SCHEMBL6295248 | 0.87 | F10 (0.54) | F10PRSS1F2PLGPROC | |
| SCHEMBL6281579 | 0.85 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6283268 | 0.85 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6278829 | 0.85 | F10 (0.52) | F10PRSS1F2PLGPROC | |
| SCHEMBL6277852 | 0.84 | F10 (0.70) | F10PRSS1F2PLGPROC | |
| SCHEMBL6281910 | 0.84 | HTR7 (0.53) | F10PRSS1F2PLGHTR7 | |
| SCHEMBL6275362 | 0.83 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL7116028 | 0.82 | F10 (1.00) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |