Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.53 |
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | PROC | P04070 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285012 | 0.86 | F10 (0.53) | F10PRSS1F2PLGPROC | |
| SCHEMBL6281885 | 0.85 | F10 (0.55) | F10PRSS1F2PLGPROC | |
| SCHEMBL7117364 | 0.85 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL7121890 | 0.83 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL6283410 | 0.82 | F10 (0.50) | F10PRSS1F2PLGPROC | |
| SCHEMBL6279097 | 0.82 | F10 (0.50) | F10PRSS1F2PLGPROC | |
| SCHEMBL6275428 | 0.82 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL6280036 | 0.81 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL6280139 | 0.81 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL6282865 | 0.81 | F10 (0.51) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |