Sugi Predict

Sugi Predict / Compounds / SCHEMBL628335

SCHEMBL628335

SCHEMBL628335

O=c1cc(C(F)(F)F)[nH]c(=O)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.44
▸ KDM4E B2RXH2 7/20 0.41
▸ ALDH1A1 P00352 5/20 0.40
▸ LMNA P02545 2/20 0.40
▸ YTHDF3 Q7Z739 1/20 0.39
▸ YTHDF1 Q9BYJ9 1/20 0.39
▸ YTHDF2 Q9Y5A9 1/20 0.39
▸ NOTUM Q6P988 1/20 0.38
▸ HPGD P15428 2/20 0.38
▸ CYP2C9 P11712 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ CYP2C19 P33261 1/20 0.36
▸ CRHBP P24387 1/20 0.35
▸ CRHR2 Q13324 1/20 0.35
▸ AR P10275 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29707614 0.98 CA1 (0.43) CA1KDM4EALDH1A1LMNAYTHDF3
SCHEMBL30839876 0.82 CA1 (0.46) CA1ALDH1A1LMNAYTHDF3YTHDF1
SCHEMBL29779360 0.82 CA1 (0.41) CA1KDM4EALDH1A1LMNAYTHDF3
SCHEMBL11726927 0.76 CA1 (0.44) CA1KDM4EALDH1A1LMNAYTHDF3
SCHEMBL7764663 0.76 CA1 (0.56) CA1KDM4EALDH1A1LMNAYTHDF3
SCHEMBL25065886 0.74 KDM4E (0.46) KDM4EALDH1A1LMNANOTUMHPGD
SCHEMBL29779364 0.74 FABP4 (0.39) CA1KDM4EALDH1A1LMNAHPGD
SCHEMBL10443999 0.74 KDM4E (0.37) KDM4EALDH1A1LMNANOTUMHPGD
SCHEMBL4890761 0.73 CA1 (0.46) CA1ALDH1A1LMNAYTHDF3YTHDF1
SCHEMBL25072588 0.73 HPGD (0.40) KDM4EALDH1A1LMNANOTUMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246791-B Method for synthesizing 6-trifluoromethyl uracil and intermediate thereof 内蒙古世杰化工有限公司 2024-11-05 — — CN claimed
CN-115246791-A Method for synthesizing 6-trifluoromethyl uracil and intermediate thereof 四川奥兰多化工有限公司 2022-10-28 — — CN claimed
EP-4038054-A1 PYRIMIDINEDIONE DERIVATIVES Bayer Aktiengesellschaft (DE) 2022-08-10 — — EP claimed
CN-110343205-A Side group functionalized polyisobutylene base thermoplastic elastomer and preparation method thereof 北京化工大学 2019-10-18 — — CN claimed
US-10038218-B2 Salts of N-containing heterocyclic anions as components in electrolytes SOLVAY SA (BE) 2018-07-31 — — US claimed
EP-2936607-B1 SALTS OF N-CONTAINING HETEROCYCLIC ANIONS AS COMPONENTS IN ELECTROLYTES SOLVAY (BE) 2017-02-22 — — EP claimed
EP-1150962-B1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS AMERICAN CYANAMID CO (US) 2004-04-28 — — EP claimed
EP-1274708-A1 HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2003-01-15 — — EP claimed
CN-1344258-A Process for producing 6- (perfluoroalkyl) uracil compound from carbamate compound BASF AG (DE) 2002-04-10 — — CN claimed
CN-1344260-A Process for prepn. of 6-(perfluoroalkyl) uracil compounds from urea compounds BASF AG (DE) 2002-04-10 — — CN claimed
EP-1169308-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1,3-OXAZIN-6-ONES AND URACILS BASF AKTIENGESELLSCHAFT (DE) 2002-01-09 — — EP claimed
EP-1150962-A1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2001-11-07 — — EP claimed
US-6313295-B1 REACTING CARBAMATE WITH AMINE; CYCLIZATION, ALKYLATION BASF AKTIENGESELLSCHAFT (DE) 2001-11-06 — — US claimed
WO-2001079203-A1 HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-10-25 — — WO claimed
US-6191275-B1 REACTING ETHYL 3-((N,N-DIMETHYLCARBAMOYL)AMINO)-4,4,4-TRIFLUOROCROTONATE, FOR EXAMPLE WITH AMINO COMPOUNDS IN ACID OR BASE TO FORM HERBICIDES OF FORMULA 1-(OPTIONALLY ALKYL), 3-(SUBSTITUTED),6-(PERFLUOROALKYL)-1H,4H-PYRIMIDINE-2,4-DIONE AMERICAN CYANAMID COMPANY 2001-02-20 — — US claimed
US-6140270-A BY REACTING THEM WITH AN AMINE COMPOUND AND AN ACID OR BASE; HERBICIDES AMERICAN CYANAMID COMPANY 2000-10-31 — — US claimed
WO-2000049003-A1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-08-24 — — WO claimed
WO-2000049004-A1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL) URACIL COMPOUNDS FROM UREA COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-08-24 — — WO claimed
WO-2000049002-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1,3-OXAZIN-6-ONES AND URACILS AMERICAN CYANAMID COMPANY (US) 2000-08-24 — — WO claimed
WO-2000049016-A1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-08-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038218-B2 Salts of N-containing heterocyclic anions as components in electrolytes SLC28A2, SLC28A1, SLC13A3 CA1 1006/4885KDM4E 4765/4885ALDH1A1 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.