Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134798 | 0.97 | TSHR (0.60) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL10343501 | 0.97 | TSHR (0.60) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL12444566 | 0.97 | TSHR (0.60) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL27823673 | 0.97 | TSHR (0.60) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL8032580 | 0.95 | SLC22A6 (0.58) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL6557587 | 0.89 | ALDH1A1 (0.50) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL7824214 | 0.87 | PPARG (0.68) | LMNAMAPTTSHRSLC22A6GPR84 | |
| SCHEMBL23565658 | 0.86 | ACE (0.48) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL22492168 | 0.86 | TSHR (0.48) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL2691938 | 0.86 | TSHR (0.48) | LMNAABCC4MAPTTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217960-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | UNIVERSITÄT BASEL (CH) | 2024-07-04 | — | — | US | disclosed |
| US-20240217960-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | UNIVERSITÄT BASEL (CH) | 2024-07-04 | — | — | US | disclosed |
| US-20240217960-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | UNIVERSITÄT BASEL (CH) | 2024-07-04 | — | — | US | disclosed |
| CN-118202014-A | Adhesive tape | 积水化学工业株式会社 | 2024-06-14 | — | — | CN | disclosed |
| EP-4320110-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | Universität Basel (CH) | 2024-02-14 | — | — | EP | disclosed |
| CN-116547360-A | Adhesive tape | 积水化学工业株式会社 | 2023-08-04 | — | — | CN | disclosed |
| CN-116529336-A | Adhesive tape and adhesive composition | 积水化学工业株式会社 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022214701-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | UNIVERSITÄT BASEL (CH) | 2022-10-13 | — | — | WO | disclosed |
| US-20110071036-A1 | ISOELECTRIC FOCUSING BIOCHIP | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2011-03-24 | — | — | US | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217960-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | PIK3R5, PIK3R1, PIK3R2 | LMNA 4234/4885ABCC4 213/4885MAPT 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.