Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215089 | 0.91 | LMNA (0.40) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15697253 | 0.88 | CAMK2A (0.44) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15697252 | 0.88 | CAMK2A (0.44) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15697256 | 0.86 | LMNA (0.46) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15697257 | 0.86 | LMNA (0.46) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL10172465 | 0.82 | TSHR (0.44) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15721706 | 0.81 | TSHR (0.56) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL18073440 | 0.81 | TSHR (0.56) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL22994951 | 0.81 | LMNA (0.32) | TSHRLMNAPMP22HDAC11GABRR3 | |
| SCHEMBL14963645 | 0.81 | LMNA (0.46) | TSHRLMNAALDH1A1HDAC3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933361-B2 | Thermally re-mendable cross-linked polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040014933-A1 | Thermally re-mendable cross-linked polymers | NATIONAL SCIENCE FOUNDATION | 2004-01-22 | — | — | US | disclosed |