Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.49 |
| ▸ | PPARG | P37231 | 16/20 | 0.49 |
| ▸ | RXRB | P28702 | 10/20 | 0.49 |
| ▸ | RXRG | P48443 | 10/20 | 0.49 |
| ▸ | RARA | P10276 | 8/20 | 0.49 |
| ▸ | RARB | P10826 | 8/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284144 | 1.00 | RXRA (0.49) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6279649 | 0.93 | RXRA (0.49) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6281795 | 0.93 | RXRA (0.54) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6281790 | 0.93 | RXRA (0.54) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6279651 | 0.93 | RXRA (0.49) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6279448 | 0.90 | RXRA (0.41) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6279454 | 0.90 | RXRA (0.41) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6281312 | 0.88 | RXRA (0.44) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6278769 | 0.85 | PPARG (0.41) | RXRAPPARGRXRBRXRGRARA | |
| SCHEMBL6278771 | 0.85 | PPARG (0.41) | RXRAPPARGRXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |