Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 10/20 | 0.41 |
| ▸ | MAOB | P27338 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366190 | 0.84 | KDM4E (0.82) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL22451559 | 0.81 | MAOB (0.64) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL11477365 | 0.80 | KDM4E (0.67) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL6825249 | 0.76 | MAOB (0.66) | MAOAMAOB | |
| SCHEMBL20165113 | 0.76 | KDM4E (0.53) | KDM4EHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL22714471 | 0.75 | KDM4E (0.68) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL67590 | 0.74 | KDM4E (1.00) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL24357640 | 0.74 | KDM4E (0.51) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL29546224 | 0.74 | KDM4E (0.51) | KDM4EHTTMAOAMAOBALDH1A1 | |
| SCHEMBL24357642 | 0.73 | KDM4E (0.50) | KDM4EHTTMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005094833-A1 | NOVEL N-SUBSTITUTED DIHYDROBENZOTHIEPINO, DIHYDROBENZOXEPINO AND TETRAHYDRO BENZOCYCLOHEPTA INDOLES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-13 | — | — | WO | disclosed |